Multi-center diffusion-weighted MRI validation for 0.35T MR-Linac
Authors: Siamak Nejad-Davarani, Natalia Lutsik, Kathryn Mittauer, Nema Bassiri-Gharb, Joseph Weygand, Tess Armstrong, Shyam Pokharel, Suresh Rana, Hui Wang, Alonso Gutierrez, Michael Kasper, Eric Mellon
From Paper: “MR-linac (MRL)-based radiotherapy allows daily anatomical and physiological imaging for adaptive treatment. Apparent diffusion coefficient (ADC) derived from diffusion-weighted imaging (DWI) is a quantitative biomarker correlated with tumor cellularity and response. Verifying ADC repeatability and reproducibility across centers is key for multi-center physiological adaptive radiotherapy trials on low-field MRLs.”
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